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小剂量短疗程抵克立得对ADP诱导的血小板聚集性的影响

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摘要 采用开放型单向序贯设计,检测了小剂量、短疗程抵克立得治疗对ADP诱导的血小板预售性的影响。方法为受试者在治疗期间每日1次服用抵克立得250mg,共治疗3周;治疗前后分别测定ADP诱导的最大血小板聚集率。结果显示,这种方法能够有效地抑制ADP诱导的血小板聚集,值得临床上进一步研究和应用。
作者 刘明宇
出处 《哈尔滨医科大学学报》 CAS 1998年第4期261-264,共4页 Journal of Harbin Medical University
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  • 1Geut M,Blakeley JA,Easton JD,et al.The Canadian-American ticlopidine study(CATS)in thromboembotic stroke,Lancet,1989;1:1215.
  • 2Hass WK,Easton JD,Adams HP,et al.A randomised trial comparing ticlopidine hydrochloride with aspirin for the prevention of stroke in high risk Patients.N Engl J Med,1989;321:501.
  • 3Janzon L,Bergquist D.Boberg J,et al.Preventionof myocardial infarction and stroke in patiemts with intennittent elaudieation:effects of tiolopidive,Results from STIMS,the Swedish tiolopidine multicentre study.J Intern Med,1990;227:201.
  • 4Balsano F,Rizzon P,Violi F,et al.vntiplatelet treatment with ticlopidine in unsteble argina:a controlled multicenter clinical trial.Circulation.1990;82:17.
  • 5Yuan J,Li Y,Zhang M,et al.The effect of ticlopidine on platelet aggregation and hemorrheology for the aged patients with common thrombotic disorders.Chin J Phath,1992;8:463.
  • 6Zheng Q.The clinical results of ticlopidine in patients with acute myocardial infarction,N Chin Med,1994;25:292.
  • 7Run C,Zhang C,He Y,et al.The effects of ticlopidine in patients with stroke.Nat Med J Chin,1991;71:408.
  • 8Roth GJ,Stanford N,Majerus PW.Acatyation of prostaglandin synthase by aspinim. Proc Natl Acad Sci,1975;72:3073.
  • 9Dewitt DC,Smith WL.Primary structure of prostaglandin G/H synthase from aheep vesicular gland detennined from the complementary DNA sequence.Proc Natl Acad Sci,1988;85:1412.
  • 10Funk CD,Funk LB,Kennedy ME,et al.Human platelet erythroleukemia cell prostaglandin C/H synthase:cDNA cloning,expression,and gene chromosomal as signment,FASEB J,1991;5:2304.

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