喹诺酮类抗生素临床应用态势及合理用药

The Progress and Clinical Application of Ratinal Drug Use about Quinolone Antibiotics

喹诺酮类(QNS)药物是一类分子中具有喹诺酮或萘啶结构的人工合成抗菌化合物,是近年来迅速发展起来的抗菌药物。具有抗菌谱广、抗菌力强、结构简单、给药方便,与其他常用抗菌药物无交叉耐药性以及价格便宜等特点,愈来愈受到各国的重视,在临床上的应用越来越广泛。但是不容忽视的是该类药物所引起的不良反应及禁忌证亦多,临床医务人员必须熟悉这些药物,既充分发挥这些药物的治疗作用,又可防止药源性疾病的发生。

Quinolones is in a kind of member has Quinolones the naphthyridine structure synthesized antibacterial compound, was the recent years rapidly expand antibiotics. Has the antibacterial spectrum broadly, the antibacterial strength to be strong, the structure simple, is convenient to the medicine, with other commonly used characteristics and so on antibiotics not cross-tolerance as well as price small advantage, receives various countries＇ more and more value, the application is getting more and more widespread on clinical. What but is not allow to neglect is this kind of medicine causes the untoward effect and the taboo card are also many, the clinical medical personnel must be familiar with these medicines, both displays these medicines fully the therapeutic action, and may prevent the medicine source disease＇s occurrence.