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肥大细胞在幽门螺杆菌相关性胃炎中的作用

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摘要 目的探讨肥大细胞(MC)在幽门螺杆菌(Hp)相关性胃炎中的作用。方法选择200例行胃镜检查的慢性胃炎患者,取胃窦黏膜分别行组织病理学HE染色及Hp检查(快速尿素酶、改良G iem sa染色)、改良甲苯胺兰染色,分别计算黏膜及黏膜下的完整和脱颗粒MC数。结果MC计数在Hp阳性和Hp阴性组间无统计学差异(P>0.05),但前者黏膜内MC脱颗粒者明显多于后者(P<0.01);MC计数在活动性炎症组显著高于非活动性炎症组(P<0.01)。结论MC可能在Hp相关性胃炎的发生发展中起重要作用。
出处 《山东医药》 CAS 北大核心 2009年第25期43-44,共2页 Shandong Medical Journal
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