支气管激发试验在慢性咳嗽及不典型哮喘中的诊断价值

Diagnostic Value of Bronchial Provocation Test in Asthmatic Patients with Atypical Symptom and Chronic Cough

目的探讨支气管组胺激发试验在慢性咳嗽及不典型哮喘中的诊断价值。方法对523例慢性咳嗽及不典型哮喘患者行支气管组胺激发试验,测定其气道高反应性(AHR)。结果523例患者支气管组胺激发试验阳性313例,阳性率59%,其中:重度AHR35例,中度AHR83例,轻度AHR101例,极轻度AHR94例。结论支气管组胺激发试验是不典型哮喘关键有效的诊断方法,对慢性咳嗽具有重要鉴别诊断意义,应及时进行检查,以便早期作出诊断。

Objective To investigate the diagnos tic value of bronchial provocation test for chronic cough and atypical asthma. Methods Bronchial histamine provocation test were conducted on 523 patients with chronic cough and atypical asthma, whose airway hyperreactivity （AHR） were subsequently measured. Results 313 patients were positive in bronchial provocation test, with 35 patients in serious AHR, 83 patients in medium AHR, 101 patients in slight AHR, and 94 patients in very slight AHR. The total positive rate was 59%. Conclusion Bronchial provocation test is a effective method to diagnose atypical asthma, which is of highly differential diagnostic significance for chronic cough.