2007年药品不良反应报告分析

Retrospective Analysis of ADR Reports in Our Hospital in 2007

目的促进药品不良反应(ADR)监测报告工作的开展。方法对内江市第二人民医院2007年收集到的227例ADR报告进行统计、分析。结果ADR涉及的药物94种,其中抗感染药物最多(108例);以头孢菌素类较高(29例);给药途径以静脉给药最多(201例);ADR累及器官或系统主要为消化系统和皮肤及其属器官。结论临床应重视ADR的监测和报告工作,以减少和避免不良反应的发生。

Objective To facilitate the monitoring and reporting of adverse drug reaction（ADR）. Methods A total of 227 ADR case reports collected in 2007 were analyzed statistically. Results The drugs induced ADR totaled 94 kinds. Of the 227 ADR 108 cases was induced by anti-infective drugs, followed by Chinese drug preparations （21 cases） and antitumor drugs （20 cases）. 201（88.5% ） cases were induced by intravenous injection. Lesions of digestive system and skin and its appendages were the chief clinical manifestations of ADR. Cephalosporin induced ADR was highest （29 cases） accounting for 26. 8% of total ADR cases, quinolone was next accounting for 24. 1% （26 cases）. Conclusion In order to reduce and avoid the occurrence of ADR, clinical departments should attach great importance to the monitoring and reporting of ADR.