生殖道感染及支原体药物敏感情况分析

Analysis of reproductive tract infection and drug susceptibility of mycoplasma

目的了解妇产科门诊女性生殖道感染情况及支原体对药物敏感分析,指导临床合理用药。方法收集整理了我院妇产科门诊患者的泌尿生殖道标本检查白带常规、淋病奈瑟菌(N.gonorrhoeae)培养、支原体(Mycoplasma)培养及药物敏感、衣原体(Chlamydia)检测的情况。结果假丝酵母菌(Candida)感染率为11.08%;滴虫感染率为1.96%;淋病奈瑟菌感染率1.49%;衣原体感染率0.83%;支原体感染率45.19%;解脲脲原体(Uu)感染率41.48%,药敏结果显示其对强力霉素和美满霉素敏感率最高,对临床使用普遍的阿奇霉素敏感率仅为35.29%。结论淋病奈瑟菌感染、支原体感染较以前报道有升高趋势,主要以Uu为主,其耐药率逐年增高,应引起高度重视。

Objective To investigate female reproductive tract infection and Mycoplasma drug sensitivity in obstetrics clinic,it might be helpful to guide our drug use rationally in clinical. Methods Obstetrics and Gynecology outpatients urogenital tract specimens fi＇om our hospital were collected to carried out routine examination of leucorrhea, Neisseria Gonorrhoeae cuhure, Mycoplasma culture and drug susceptibility, detection of Chlamydia. Results Candida infection rate was 11.08%; Trichomonas infection rate was 1.96% ; Neisseria gonorrhoeae infection rate was 1.49%; Chlamydia infection rate was 0.83%; Myeoplasma infection rate was 45.19%; Ureaplasma urealvticum （Uu） infection rate was 41.48%, and the results of drug susceptibility showed that it was most sensitive to doxycycline and minocycline and the sensitivity to azithromycin which was widely used in clinical decreased to 35.29%. Conclusion Neisseria gonorrhoeae and mycoplaslna infection rate were increased than reported. It was mainly Uu-dominated and we should pay great attention to it for the gradually increased drug-resistance.