幼龄和老龄小鼠肝心组织中几项生化指标变化的研究

Variations Biochemical Indexes in the Hepatic and Cardiac Tissues of Young and Aged Mice

幼龄和老龄鼠肝、心组织中过氧化脂质（LPO）,超氧化物歧化酶（SOD）、谷胱甘肽过氧化物酶（GSH-Px）测定表明,幼龄鼠肝组织中LPO明显低于老龄鼠,心组织中LPO两组比较不显著（P＜0.01、P＞0.05）;幼龄鼠肝、心组织中SOD活力显著高于老龄鼠（P＜0.001、P＜0.01）;而GSH-Px活力明显低于老龄鼠（P＜0.01P＜0.01）。

The lipidhydroperoxides (LPO), superoxide dismutase (SOD) and Glutathione peroxidase (GSH - Px) in the hepatic and cardiac tissues in young and aged mice were detected. The results showed that the activity of GSH - Px in Hepatic and cardiac tissues of the young mice was markedly lower (P < 0.01 and P < 0.01 ) than that of the aged mice and the LPO in livers of the young mice was also lower (P < 0.01 ) than than of the agedmice, hut the LPO difference in cardiac tissues between young miceand aged mice was of no statistic significance (P > 0.05 ). On the contrary, the activity of SOD in hepatic and cardiac tissues of the young mice was obviously higher (P < 0.001 and P < 0.01 ) than that of the aged mice, while the GSH-Px Vitality was markedly lower than that of the aged mice.