摘要
原发性硬化性胆管炎(PSC)是一种自身免疫性疾病,其发病机制尚不明确。PSC诊断的金标准是内窥镜下逆行胆管造影技术(ERCP)及磁共振胰胆管造影术(MRCP)。PSC的治疗方法很多,包括药物治疗和肝移植。药物多推荐熊去氧胆酸,但效果欠佳。目前认为肝移植仍是治愈PSC的惟一选择。本文对PSC的研究及治疗进展作一概述。
Primary sclerosing cholangitis （PSC） is an autoimmune disease with unknown etiology. Its diagnosis primarily based on endoscopic retrograde cholangiography （ERCP） and magnetic resonance cholangiography （MRCP）. Current therapies include medical therapy and liver transplantation. Medical therapy has recommended ursodeoxycholic acid, however, the effect is not good enough. Liver transplantation is still the only choice to cure PSC so far. The present review stated the recent achievements on the research and management of PSC.
出处
《胃肠病学和肝病学杂志》
CAS
2009年第7期587-590,共4页
Chinese Journal of Gastroenterology and Hepatology
关键词
原发性硬化性胆管炎
UDCA
肝移植
Primary sclerosing cholangitis
Ursodeoxycholic acid
Liver transplantation
