摘要
目的探讨受检者的自身因素对在体肝脏^1H—MRS自动预扫描中匀场和抑水效果的影响。方法回顾性分析57例行肝脏^1H—MRS检查受检者资料,其中正常受检者35名、慢性乙型肝炎5例、脂肪肝14例、脂肪肝合并慢性乙型肝炎3例。把受检者按是否抑水率(WS)≥90%及是否匀场线宽(LW)〉20Hz分别分为2组,分别采用两独立样本的t检验比较2组的一般情况如身高、体重、体质量指数(BMI),采用卡方检验比较脂肪肝组与非脂肪肝组达到较好的LW和WS效果的比率。结果抑水较好组47例和抑水不好组10例比较,平均身高[分别为(164.7±8.0)和(170.5±3.7)cm]、体重[分别为(61.8±10.4)和(73.4±5.4)kg]、BMI[分别为(22.7±3.2)和(25.2±1.3)kg/m^2]及LW[分别为(17.7±3.7)和(24.6±6.3)Hz],差异均有统计学意义(t值分别为-3.488、-3.415、-4.002和-3.327,P值均〈0.05)。匀场较好组41例和匀场不好组16例比较,体重[分别为(62.2±11.6)和(68.1±6.1)kg],BMI[分别为(22.8±3.4)和(24.2±1.9)kg/m^2],WS[分别为(93.0±2.7)%和(86.1±8.5)%],差异均有统计学意义(t值分别为-2.516、-2.024和3.213,P值均〈0.05)。脂肪肝组17例巾,7例自动匀场LW≤20Hz,无脂肪肝组40例中,34例自动匀场LW≤20Hz,2组间差异有统计学意义(Х^2=11.347,P〈0.05)。脂肪肝组17例中,WS〈90%者7例,无脂肪肝组40例中,无WS〈90%患者,两者差异有统计学意义(Х^2=28.536,P〈0.05)。结论肝脏的脂质沉积对^1H—MRS匀场及抑水存在负性影响,体重及BMI大的受检者达到良好的匀场和抑水效果预期成功率低。
Objective To characterize the clinical factors which influence water suppression and auto-shimming line width for liver 3.0 T ^1H-MRS. Methods Fifty-seven cases with liver ^1H-MR spectroscopy(^1H-MRS) were retrospectively studied, including chronic type B hepatitis (n = 5), fatty liver (n=14), chronic type B hepatitis combining fatty liver (n = 3) and normal situation (n : 35). Independent t test was used to characterize the difference of general condition ( height, weight, body mass index etc. ) between different water suppression effect groups and between different shimming effect groups. Using Chi-square test to analyze whether water suppression rate and auto-shimming line width between fatty liver groups and non-fatty liver exist significance difference . Results By comparing WS≥ 90% ( n = 47 ) group with WS 〈 90% ( n = 10) group, the former showed smaller average height [ ( 164. 7 ± 8.0) and (170.5±3.7) cm respectively], weight [(61.8± 10.4) and (73.4 ±5.4) kg respectively], BMI [(22.7±3.2) and (25.2±1.3)kg/m^2 respectively] and LW [(17.7 ±3.7)and(24.6 ±6.3) Hz respectively ] than the latter( t = - 3. 488, - 3. 415, - 4. 002 and - 3. 327, P 〈 0. 05 ). By comparing LW ≤ 20 Hz ( n = 41 ) group with LW 〉 20 Hz ( n = 16 ) group, the former showed better water suppression rate [ (93.0 ±2. 7)% and (86. 1 ±8.5)% respectively] than the latter(t =3. 213 ,P 〈0. 05), whereas larger weight[(62.2 ± 11.6) and (68.1 ± 6.1) kg respectively] and BMI[(22.8 ± 3.4) and (24.2 ±1.9)kg/m^2 respectively] (t = -2. 516, -2. 024,P 〈0. 05). LW≤20 Hz in the fatty liver and non-fatty liver group was 7/17 and 34/40, respectively ( Х^2 = 11. 347, P 〈 0. 05 ). WS 〈 90% in the fatty liver and non-fatty liver group was 10/17 and 0/44, respectively (Х^2 = 28. 536, P 〈 0. 05 ) . Conclusion Hepatic steatosis exerts an adverse effect in water suppression and shimming.
出处
《中华放射学杂志》
CAS
CSCD
北大核心
2009年第7期739-742,共4页
Chinese Journal of Radiology
基金
广东省自然科学基金资助项目(5001199)
广东省科技计划资助项目(2005810401040)
广东省医学科学技术研究基金资助项目(A2005018)
国家自然科学基金项目资助(30800269)广东省人民医院放射科刘辉、王秋实、谭绍恒、萧远球及汕头大学第二附属医院放射科关计添在实验设计方面给予帮助
关键词
肝
脂肪肝
磁共振波谱学
Liver
Fatty liver
Magnetic resonance spectroscopy