摘要
为开拓一种治疗溃疡性结肠炎的中药制剂,将78例溃疡性结肠炎(UC)分层随机分为两组,治疗组以肠炎清治疗,对照组以柳氮磺胺吡院治疗。治疗60d后结果发现,治疗组临床证候总显效率为84.61%,对照组为35.90%(P<0.01),总有效率治疗组为89.74%,对照组58.97%(P<0.01);两组肠粘膜的总显效率治疗组为69.23%,对照组15.38%(P<0.01),总有效率治疗组为87.18%,对照组56.41%(P<0.01)。认为不论轻、中、重型的UC患者,肠炎清的疗效均优于柳氮磺胺吡啶。
78 patients with ulcerative colitis were randomly divided into two groups,therapeutic group (39 cases) treated by changyanqing decoction (CRQD) using enema and peroralmethods, and control group (39 cases) by azulfidine for 60 days. The results showed the clinicalcure rate and total effective rate in therapeutic group were respectively 84. 61%, 89. 74%;but 35. 90%, 58. 97% in control group (P < 0. 01 ). The cure rate of intestinal mucosapathological change and total effective rate in therapeutic group were 69. 23%, 87. 18% ; but 15.38 %, 56. 41 % in control group (P<0. 01 ). It suggested that curative effect of CYQD is superiorto that of azulfidine.
基金
广东省科委九五重点科技资助