刺五加注射液治疗糖尿病性周围神经病变观察

Observation on Diabetic Peripheral Neuropathy Treated with Acanthopanax Root Injection

以刺五加注射液治疗糖尿病性周围神经病交４５例，并与静滴生理盐水１８例进行疗效对比，结果治疗组显效率４８．９％，总有效率８９．９％；对照组分别为５．６％、３８．９％；经统计分别为Ｐ＜０．０１、Ｐ＜０．０５。两组治疗后生化指标的变化为：胆固醇变化无差异性（Ｐ＞０．０５），而甘油三脂、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇与空腹血糖的变化均有显著差异（Ｐ＜０．０１、Ｐ＜０．０５、Ｐ＜０．０５、Ｐ＜０．０１）。提示刺五加注射液对改善糖尿病性周围神经病变、降低血脂和血糖有确切疗效，且未见副作用。

cases of diabetic peripheral neuropathy were treated with acanthopanax root injection and, at the same time 18 with normal saline as contrast. The result was that the obvious effect was 48. 9% and the total effect rate was 89. 9% in treatment group; 5. 6% and 38.9% in control one(P<0. 01 ,P<0. 05). The change of cholesterol has no significant difference, but triglyceride, low density, lipoprotein, high density lipoprotein and fasting blood-glucose significant difference between these two groups(P<0. 01,P<0. 05,P<0. 05, P <0. 01). It showed this injection has good efficacy for improving the pathological process of peripheral neuropathy and no side effect.