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乳腺浸润性小叶癌女性生殖道转移3例报道并文献复习 被引量:4

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摘要 目的乳腺浸润性小叶癌转移到女性生殖道罕见,探讨其临床病理特点及鉴别诊断要点。方法结合文献分析报道3例乳腺小叶癌女性生殖道转移,并进行临床资料、组织学和免疫组化标记观察。结果3例患者在乳腺癌切除后,出现腹部不适及包块、不规则阴道出血,行姑且性子宫切除和(或)输卵管卵巢切除术。组织学见卵巢、输卵管、子宫内膜及肌层和平滑肌瘤内单线状癌细胞浸润生长,破坏卵巢白体,浸润输卵管黏膜和子宫内膜间质,输卵管腺上皮和宫内膜腺体完好。免疫组化标记:瘤细胞ER、PR(+),E-cad-herin(-),GCDFP-15、CK(+)。结合乳腺癌切片与转移癌形态基本一致。结论乳腺浸润性小叶癌女性生殖道转移具有组织学显著特征,根据病史及免疫组化标记可明确诊断。
出处 《临床与实验病理学杂志》 CAS CSCD 北大核心 2009年第3期318-319,共2页 Chinese Journal of Clinical and Experimental Pathology
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