扶桑花乙酸乙酯不溶物HR-4的生物学作用研究

Studies on Biological Action of Ethyl acetate Insoluble Fraction of

扶桑花乙酸乙酯不溶物ＨＲ－４对离体子宫和心血管系统的影响．结果表明，１．ＨＲ－４对小鼠离体子宫有明显的收缩作用，该作用可被异丙嗪完全阻断；而消炎痛可部分抑制该兴奋作用．２．ＨＲ－４对离体蛙心的心肌收缩力有抑制性影响，且ＨＲ－４对心肌收缩幅度的影响较对心率的影响更为明显．

Ethyl acetate insoluble fraction of Hibiscus rosasinensis flowers has been studied for the biological action.The results show that:1) this fraction has stimulating action on the uterus of mouse in vitro,and the action can be blocked by promethazine and partly inhibited by indomethacin.2) the fraction can reduce the heart rate and heart contract amplitude of frog in vitro.