早期龋齿的激光感生荧光光谱探测(英文)

Early caries detection by laser induced fluorescence spectrum

提出了一种利用低功率He-Nelaser(λ=632.8nm,2.0±0.1mW)光学无损诊断早期龋齿的方法,并与探诊方法、光子波动非线性转换方法(PNC)以及DIAGNodent龋齿诊断仪进行了比较。这种探测方法不使用滤光片,采集荧光光谱的能力与PNC方法和DIAGNodent龋齿诊断仪不同,所获得的牙齿特征光谱含有大量的关于牙齿成分、结构、空间构象等的信息。该项研究在离体牙齿上进行。牙齿的特征光谱由后向散射光、反射光、自体荧光3个部分组成,对自体荧光光谱的特征频率进行分析可以确定牙齿化学成分的改变,而对反斯托克斯荧光光谱进行分析则可以评价牙齿组织结构和形态学的变化。初步研究结果表明:文中方法在定量诊断各种龋齿方面极具应用潜力,对于探测早期龋齿、健康牙齿的表面损坏更敏感。

A non-invasive method adapted for optical diagnosis of early caries by using low-power He-Ne laser （λ=632.8 nm, 2.0±0.1 mW） was represented, and the comparison with the dental explorer, Photon undulatory Non-linear Conversion （PNC） method and DIAGNodent was given. This method without light filter, differed from the DIAGNodent and PNC method in its ability for registering fluorescence spectrum. The characteristic spectrum of dental tissue contained rich information such as dental components, structure, spatial conformation. The research was conducted in vitro. Three parts of characteristic spectrum including backscattering, reflection and auto-fluorescence were analyzed. It enables not only to evaluate chemical changes in tooth by analyzing characteristic frequencies of auto-fluorescence spectrum, but also to estimate structure and morphological changes in tissue by means of anti-stoke＇s fluorescence spectrum. Preliminary results show that this method has a potential application in the quantitive diagnosis of various stages of dental caries and is more sensitive for detecting early caries and the surface damage of health enamel.