1Medzhitov R,Presyon-hurlburt P,Janeway CA Jr,et al.A human homologue of the Drosophila Toll protein signals activation of adaptive immunity.Nature,1997,388:394-397.
2Janeway CA Jr,Medzhitov R.Innate immune recognition.Annu Rev Immunol,2002,20:197-216.
3Akira S,Uematsu S,Takeuchi O.Pathogen recognition and innate immunity.Cell,2006,124:783-801.
4Martin MU,Wesche H.Summary and comparison of the signaling mechanisms of the Toll/interleukin-1 receptor family.Biochim Biophys Acta,2002,1592:265-280.
5Ohashi K,Burkart V,Flohe S,et al.Cutting edge:heat shock protein 60 is a endogenous ligand of the toll-like receptor-4 complex.J Immunol,2000,164:558-561.
6Kurt Jones EA,Popova L,Kwinn L,et al.Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus.Nat Immunol,2000,1:398-401.
8Fitzgerald KA,Pulsson MC,Demott EM,et al.MAL(MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction.Nature,2001,413(6851):78-83.