期刊文献+

氯沙坦和贝那普利联合治疗糖尿病肾病的临床研究 被引量:1

下载PDF
导出
摘要 目的探讨氯沙坦和贝那普利联合治疗糖尿病肾病的临床效果。方法选择72例内分泌科门诊及住院病例,随机分为观察组和对照组,观察组应用氯沙坦和贝那普利联合治疗,对照组单用贝那普利治疗,比较两组疗效和不良反应。结果观察组治疗总有效率为94%,对照组治疗总有效率为56%,差异有统计学意义(P<0.05)。结论氯沙坦和贝那普利联用治疗DN能明显提高疗效,而且耐受性和安全性较好,值得推广应用。
作者 冯飞
出处 《中国实用医药》 2009年第19期181-182,共2页 China Practical Medicine
  • 相关文献

参考文献1

二级参考文献11

  • 1王琳.血管紧张素转换酶抑制剂在早期DN时的应用[J].德国医学(Ger Med),1995,12(3):173-5.
  • 2Urata H, Boehm KD, Philip A,et al.Cellular localization and regional distribution of an angiotensin Ⅱ-forming chymase in the heart[J].J Clin Invest,1993,91(4):1269-81
  • 3Azizi M, Chatellier G, Guyene T, et al. Additive effects of combined angiotensin-converting enzyme inhibition and angiotensin Ⅱ antagonism on blood pressure and rennin release Ⅰ sodium depleted normotensives[J]. Circulation, 1995, 92(9): 825-34.
  • 4Olsen ME, Thomsen T, Hassager C, et al. Hemodynamic and renal effects of indomethacin in losartan-treated hypertensive individual[J]. Am J Hypertens, 1999, 12(2-1): 209-16.
  • 5Andersen S, Tamow L, Rossing P, et al. Renoprotective effects of angiotensin Ⅱ receptor blokade in type Ⅰ diabetic patients with diabetic nephropathy[J]. Kidney Int, 2000, 57(2): 601-6.
  • 6Junaid A, Rosenberg ME, Hostetter TH. Interaction of angiotensin Ⅱ and TGF-beta Ⅰ in the rat remnant kidney[J]. J Am Soc Nephrol,1997, 8(11): 1732-8.
  • 7Kato S, Luyckx VA, Ots M, et al. Renin-anglotensin blokade lowers MCP-Ⅰ expression in diabetic rats[J]. Kidney Int, 1999, 56(3):1037-48.
  • 8Singh R, Alavi N, Singh AK, et al. Role of angiotensin Ⅱ in glucoso-induced inhibition of mesangial matrix expansion[J]. Diabetes,1999, 48(10): 2066-73.
  • 9Russo'D, Pisani A, Balletta MM, et al. Addictive antiproteinuric effect of converting enzyme inhibitor and losartan in nor mote naive patients with IgA nephropathy[J]. Am J Kidney Dis, 1999, 33(9):851- 6.
  • 10张颖娟,周启林.老年糖尿病肾病中药治疗前后血脂、过氧化物歧化酶的变化[J].第一军医大学学报,2001,21(1):42-43. 被引量:3

共引文献12

同被引文献28

二级引证文献22

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部