福建省自然人群丙型肝炎感染流行特征

The Epidemiologic Feature of HCV Prevalence in Fujian

为了解福建省人群丙型肝炎流行特征，于1992年进行丙型肝炎感染的血清流行病学调查。采用多阶段分层整群随机抽样法，采集福建省疾病监测点自然人群的1237户家庭中3809例血清标本。应用UBIEIA法检测。结果显示HCV标化流行率为3．99％，男性3．63％，女性4．25％；城市3．12％，农村460％；10岁以下较低，峰值在20岁左龄组。年龄问、性别间、城乡间无差异；地区间差异显著，最高为6．08％，最低1．39％。家庭内传播并不重要，无家庭聚集性现象。存在HCV与HAV、HBV、HEV的重叠感染。丙肝感染与输血史、肝病史无显著相关。95．4％丙肝感染者无输（受）血史。结果提示福建省自然人群HCV传播主要经输血以外途径散发性感染。

To investigate the epidemiologic features of HCV prevalence, a sero-epidemiological survey onHCV infection has been carried out in Fujian since 1992. Using stratified multistage random cluster sampling,3809 serum samples collected from 1237 families in the surveillance points were tested by UBI HCV EIA kit. Theresults showed that the prevalence rate was 3. 99%. The rate in male and female was 3. 63% and 4. 25%, in urban and rural 3. 12% and 4. 60% respectively (P>0. O5). There was lower rate in chi1dren aged under 10 years.The highest rate was in 20-24 years old. The rate for different areas were ranged from 1. 39% to 6. 08% (P<0. 05). The transmission of intra-families was not important and no clustering in families. The super-infection ofHCV with HAV, HBV and HEV were existed. HCV infection and the blood transfusi0n and the hepatitis historywas not significant correlation. It suggests that the HCV transmission among the population in Fujian is mainlysporadic infecxion.