心理应激对不同行为类型者血浆环核苷酸含量影响的研究阿发Ⅰ.期终考试对不同行为类型医学生血浆环核苷酸含量影响的研究

The effect ofa final examination on levels of plasm cyclic nucleotid e in different behavior type medical students

目的 了解不同行为类型的医学生应激前后血浆 CN含量变化 ,为探讨心理行为因素引发冠心病中介机制的研究提供前瞻性资料。方法 用前瞻性方法研究解剖学期终考试对不同行为类型的医学生血浆环核苷酸 (CN)含量的影响。结果 应激前 ,TABP医学生血浆 c AMP含量显著高于 TBBP医学生 (P <0 .0 0 1) ;应激后 ,TABP和 TBBP医学生血浆 c AMP均显著下降 (P <0 .0 0 1) ,其下降程度前者明显大于后者 ,(P <0 .0 0 1) ;血浆 c GMP含量均下降 ,但无差异 (P >0 .0 5 ) ,c AMP/c GMP比值 TABP和 TBBP两者均显著下降 (P <0 .0 0 0 1)。但下降程度 TABP和 TBBP之间无显著差异 (P >0 .0 5 )。结论 考试应激对医生生血浆 c AMP含量的影响 TABP者显著大于

Objective To understand the change on plasm cyclic nucleotide levels inindividuals of different behavior type.To provide pr ospective data for exploring the mechanism of psycholgical factorsinducing CHD. Method The effects of a final examination in anatomy on le vels of plasmcyclic nucleotide in the first year medical students of different behavior type were observed in this prospectivestudy.Results Before the stress,the plasm cAMP levels in TABP students are significantlyhigher than the levels in TBBP students(P<0.001).After the stress,the level s of plasm cAMP in both TABP and TBBPstudents decreased siginificantly.The leve ls in TABP students are significantly lower than the levels in TBBP students(P<0.0001).whereas in both TABP and TBBP students,the ratio of cAMP/cGMP decrea sedsignificantly(P<0.0001) ,but both between did not deviated significantly((P>0.05).Conclusion The effects of stress caused by examination on the levels of pl asm cyclic nucleotide in the TABPmedical students are greater significantly tha n in the TBBP medical students.