造影确诊冠心病与心肌梗塞危险因素的比较

Comparison on risk factors of coronary angiography defined CHD with MI

比较心肌梗塞与造影确诊冠心病危险因素的异同，寻找心肌梗塞特异的危险因素．方法：以病例-病例对照研究方法对228例心肌梗塞（MI）患者和126例冠状动脉造影确诊的心绞痛（AP）患者的危险因素进行了调查和比较．结果：单因素分析结果显示，高血压病史、高血压病家族史、吸烟史、典型和不典型AP病史的OR值分别为0．64，0．52，0．55，0．04和0．06，两组间血清脂质代谢标志、吸烟量、吸烟年限和吸烟指数均无显著差异．多因素Logistic回归分析结果显示，年龄、女性、吸烟和AP症状的OR值分别为1．03，0．35，0．35和0．48．结论：年龄是MI的危险因素，而女性和AP症状可能对MI起保护作用．

Aim: To observe the difference of risk factorsbetween coronary arteriography (CAG ) defined coronaryheart disease (CHD) and myocardial infarction (MI) and tofind out specific risk or protective factors of MI. Methods:Risk factors in 228 MI cases and 126 CAG defined CHD cases were investigated by the same questionnaire and the samecriteria from 1991 to 1996. Results: Uni-variable analysisshowed that odds ratio (OR)s of history of essential hypertension (EH), family history of EH, cigarette smoking andtypical and non-typical angina pectoris were 0. 64,0. 52, 0. 55, 0. 04 and 0. 06 respectively. Index of cigarettesmoking as well as other risk factors were statistically nonsignificant. Multiple Logistic regression showed that OR ofage, female, cigarette smoking and angina pectoris were1. 03, 0. 35, 0. 35 and 0. 48 respectively. Conclusion: Ageis a risk factor of MI, while female, typical and non-typicalangina pectoris may protect CHD patients from MI.