摘要
通过插层技术合成了卵磷脂/蒙脱土(PC/MMT)纳米中间体,利用XRD、FT-IR对合成的卵磷脂/蒙脱土纳米中间体进行了表征,结果表明卵磷脂已进入了蒙脱土层间,其层间距高达6.13nm;通过溶血试验和血浆复钙试验评价了PC/MMT纳米中间体的血液相容性,试验结果表明PC/MMT纳米中间体的溶血率<5%,符合生物医学材料的标准,复钙时间较长,有良好的血液相容性;预示了其在生物医药领域的潜在应用性。
In this research, a novel nanocomposite-phosphatidylcholine/montmorillonite （PC/MMT） was prepared through solution intercalated reaction. The properties of this nanocomposites were characterized by X-ray diffraction （XRD）, Fourier transformed infrared （FT-IR）. The results showed that PC had intercalated into MMT. The basal spacing of montmorillonite is high to 6.13nm. Blood compatibility of PC/MMT nanocomposites were evaluated by haemolysis test and olasma recalcification time test （PRT）. The haemolysis rate of PC/MMT nanocomposites passed the international standard. It also had long PRT and are potential candidates for various applications in medical field.
出处
《功能材料》
EI
CAS
CSCD
北大核心
2009年第7期1163-1165,共3页
Journal of Functional Materials
基金
国家自然科学基金资助项目(20874047)
国家高技术研究发展计划(863计划)专项资助项目(2006AA032Z445)
教育部博士点基金资助项目(20050319010)
江苏省教育厅基金资助项目(JHB05-21)
关键词
蒙脱土
卵磷脂
血液相容性
montmorillonite
phosphatidylcholine
blood compatibility
