摘要
为研究急性心肌梗死（AMI）时QT间期离散度（QTD）的变化规律及其与临床的关系，对93例AMI病人进行了入院时及第4周的QTD测定，并与80例正常人对照。结果发现：（1）AMI患者入院时及第4周的QTD均大于对照组（P＜0．001）。（2）单部位MI患者入院时的QTD无明显差异，但第4周时多部位MI患者的QTD明显大于单部位MI患者（P＜0．005）。（3）AMI合并心衰、室速或室颤者QTD均明显大于无合并症者（P＜0．05或P＜0．01）。结论：AMI患者QTD明显延长，提示心肌复极存在明显不均匀性和心电不稳定性，对预测心脏病发作和猝死有重要参考价值。
In order to study the rule of QT dispersion (QTD) change during acute myocardial infarction (AMI) and its relationship to the clinical practice, it was measured in 93 patients with acute myocardial infarction on admission and the fourth week after admission, and in 80 normal subjects. The results showed that QTD in patients, at both time points, was more prolonged than that of the control group (P<0.001): QTD had no significant difference between patients with single myocardial infarction and patients with multiple myocardial infarction on admission,but QTD of the latter was more prolonged than that of the former at 4 weeks after admission (P <0.05 or P<0.01) and QTD of the dead resulting from AMI was more prolonged than that of the survived. It was suggested that the prolonged QTD indicate in patients with acute myocardial infarction and there was obvious imbalance in the repolarization of myocardium and instability of cardiac electric activity. All these changes are helpful to prediction of cardiac event and sudden death.
