5Drossman DA,Whitehead WE,Camilleri M.Irritable bowel ayndrome:a technical review for practice guideline development[J].Gastroenterology,1997,112:2120-2137.
6Pimentel M,choe EJ.Eradication of small intenstnal bacterial over growth reduces symptoms of irritable bowel syndrome[J].Am J Gastroen terol,2000,95:3503-3506.
7Collins SM,Vallance B,Barbara G,et al.Putative inflammatory and im munological mechanism in functional bowel disorders[J].Bailliere's Clin Gastroenterol,1999,13:429-436.
2[2]Yaksh TL,Hua XY,Kalcheva I,et al.The spinal biology in humans and animals of pain states generated by persistent small afferent input.Proc Natl Acad Sci USA,1999,96(10):7680-7686
3[3]Mayer EA,Collins SM.Evolving pathophysiologic models of functional gastrointestinal disorders.Gastroenterology,2002,122(7):2032-2048
4[4]Gupta V,Sheffield D,Verne GN,et al.Evidence for autonomic dysregulation in the irritable bowel syndrome.Dig Dis Sci,2002,47(8):1716-1722
5[5]Verne GN,Price DD.Irritable bowel syndrome as a common precipitant of central sensitization.Curr Rheumatol Rep,2002,4(4):322-328
6[6]Muller-Lissner SA,Fumagalli I,Bardhan KD,et al.Tegaserod,a 5-HT(4) receptor partial agonist,relieves symptoms in irritable bowel syndrome patients with abdominal pain,bloating and constipation.Aliment Pharmacol Ther,2001,15(10):1655-1666
7[7]Delvaux M,Louvel D,Lagier E,et al.The kappa agonist fedotozine relieves hypersensitivity to colonic distention in patients with irritable bowel syndrome.Gastroenterology,1999,116(1):38-45
8[8]Mertz H.Role of the brain and sensory pathways in gastrointestinal sensory disorders in humans.Gut,2002,51 Suppl 1:i29-33
9[9]Bonaz B,Baciu M,Papillon E,et al.Central processing of rectal pain in patients with irritable bowel syndrome:an fMRI study.Am J Gastroenterol,2002,97(3):654-661
10[10]Bernstein CN,Frankenstein UN,Rawsthorne P,et al.Cortical mapping of visceral pain in patients with GI disorders using functional magnetic resonance imaging.Am J Gastroenterol,2002,97(2):319-327
