妇产科围手术期预防性抗菌药物使用的干预

Rational Usage of Antibiotics Prophylaxis in Department of Obstetrics and Gynecology During Perioperative Period

目的调查临床药师对妇产科预防性抗菌药物的使用现状,促进预防性抗菌药物的合理使用。方法临床药师对267例妇产科患者预防性使用抗菌药物的情况进行回顾性分析,根据不合理使用预防性抗菌药物的情况,提出合理使用措施并参与后续206例患者临床用药指导。结果223例患者中预防性抗菌药物不合理使用率为100.00%,术后感染率为9.87%,提出合理措施后206例患者预防性抗菌药物不合理使用率为3.88%,术后感染率为1.46%(P<0.05)。结论通过临床药师对妇产科不合理使用抗菌药物的现况分析,提出相应措施,不合理使用情况明显下降,促进了抗菌药物的合理使用。

OBJECTIVE To promote clinical rational use of antibiotic prophylaxis through surveying it in Obstetrics and Gynecology Department （OG） by pharmacists. METHODS Data of 223 cases using of antibiotic prophylaxis in OG were retrospectively analyzed. According to unreasonable use of antibiotic prophylaxis, the clinical pharmacists put out reasonable measures and directed treatment in succedent 206 patients. RESULTS The rate of unreasonable use of antibiotic prophylaxis in 223 cases was 100 % and rate of infection after operation was 9.87 %. After giving intervention, the rate of unreasonable use of antibiotic prophylaxis and infection were reduced to 3.88% and 1.46%, respectively （P 〈 0. 05）. CONCLUSIONS The rate of unreasonable use of antibiotic prophylaxis is decreased markedly by clinical pharmacists＇ intervention.