金属硫蛋白(MT)与男性不育患者精浆铅镉及精子参数的研究

Metal sulfide eggs (MT) and male sterility patients seminal plasma lead and cadmium in semen parameters of research

目的探讨金属硫蛋白(Metallothionein,简称MT)与男性不育精浆铅镉、精子参数的关系。方法采用钨舟原子吸收光谱法检测患者口服金属硫蛋白前、后精浆铅Pb镉Cd的浓度;采用(computer aided semen anlysis,CASA)方法检测精子质量,分析各组数据间有无统计学意义。结果服用MT1-2个疗程前后进行统计学配对t检验:精子活率检测,密度、活率达到正常参考值的分别为46.8% P<0.05统计学上有显著差异、34.78% P<0.001统计学上有极显著差异。精子密度、精子活率的改善率分别为58.69% P<0.05统计学上有显著差异、56.52%<0.05统计学上有显著差异。结论口服MT后精子参数有不同程度的改善,对方怀孕11人占19.64%。

Objective： To explore the Metallothionein, Metallothionein （MT） referred to male infertility seminal plasma cadmium, lead the semen parameters. Methods ： tungsten light boat atomic absorption law - governing patients metallothionein oral test before and after the seminal plasma concentrations of cadmium, lead, Cd, Pb Computer aided by order, semen （CASA） method, analyzes each sperm quality data without statistical significance. Results： taking MT 1 -2 months after treatment were statistically matching t test ： sperm density detection rate of live, live the reference rate reached normal 46. 8 percent respectively, （ P 〈 0. 05 ） statistically significant difference （ P 〈 0. 001 ） 34.78%, statistically significant differences. Sperm density, sperm live rate respectively 58.69% period （ P 〈 0. 05 ） statistically significant differences, 56. 52% （ P 〈 0.05 ） statistically significant differences. Conclusion： oral MT semen parameters have different degree after the improvement of other pregnancy, 11 19. 64%.