幽门螺杆菌在成人消化性溃疡检出的探讨

Detection of heliobacter pylon in patients with peptic ulcer

目的：探讨幽门螺杆菌（HP）感染与消化性溃疡（PU）及年龄、性别的关系。方法：采用快速尿素酶和组织H-E染色法对119例PU病人进行HP感染检测，其中男性96例、女性23例，以上二种方法测定结果均阳性定为HP感染。然后将这些病例按年龄分为三组，即青年组33例，中年组78例和老年组8例。结果：HP总感染率：胃溃疡78．6％，十二指肠球溃疡63．6％，幽门管溃疡66．7％及复合溃疡62．5％，该结果与以前报道相同。各种溃疡的HP感染率在各年龄组间比较及男、女性别间比较无显著性差异（P均＞0．05）。结论：HP感染与PU关系密切，与性别无关，并不与年龄成正比上升。

Objective: To study the relationship of heliobacter pylon(HP) infection with peptic ulcer (PU) and age, sex. Methods: Using rapid arease test and H - E stain method detected HP infection in 119 patients with PU, including 96 maleand23 female. HP infection was confirmed if twO above show positive.Then,the cases were divided into 3 groups according to age: the young group(18-35 years)33 cases, the midddle-aged group(36 -59 years)78 cases and the old group(60- 70 yeare) 8 cases. Results: Total infection rates of HP were 78. 6% in gastric ulcer(GU),63 .6% in duodenal ulcer(DU), 66.7% in Pyloric ulCer and 62.5% in complex ulcer.The results were similiar to the previous reports. In three age groups and in male and female there were no significant difference (P > 0.05). Conclusion: HP infection is closely related with PU, but there is no difference between male and female .It seems that HP infection has no relevance with increase of age.