北京社区老年人轻度认知障碍与慢性病的相关性研究

Study on the relationship between mild cognitive impairment and chronic disease in aged people of Beijing community

目的探讨北京社区老年人轻度认知障碍(MCI)患病率与慢性病的关系。方法抽样调查北京城乡社区老年人1716例,比较包括高血压、心脏病、脑卒中、消化系统疾病、呼吸系统疾病等不同慢性病的老年人MCI患病率。采用logistic回归分析MCI的危险因素。结果与未患高血压、心脏病、脑卒中的老年人MCI患病率(9.3%,10.7%,10.9%)比较,患有高血压、心脏病、脑卒中等慢性病的老年人MCI患病率(18.2%,17.6%,22.6%)显著升高,差异有统计学意义(P=0.002,P=0.005,P=0.000),logistic回归分析结果显示,高血压、心脏病和脑卒中是MCI的独立危险因素(OR=2.082,95%CI:1.521～2.851,P=0.000;OR=1.633,95%CI:1.168～2.282,P=0.004;OR=2.035,95%CI:1.379～3.003,P=0.004)。结论加强心脑血管疾病的防治,对老年人认知功能的维护具有重要意义。

Objective To study the relationship between the chronic disease and mild cognitive impairment（MCI） in aged people of Beijing community. Methods 1 716 aged people in Beijing community which could represent whole Beijing were investigated and their prevalence of MCI was compared if their chronic diseases were different. Chronic diseases included hypertension, heart disease, cerebral thrombosis, diseases of respiratory system and diseases of digestive system. Results The prevalence of MCI was related with chronic diseases. The prevalence of MCI in aged people was higher when they had hypertension,heart disease and cerebral thrombosis（18. 2%, 17.6% and 22.6% respectively） as compared with those without these chronic diseases（9.3%, 10.7% and 10.9% respectively） , with significant difference （P = 0. 002, P = 0. 005 and P =0. 000 respectively）. Logistic analysis indicated that hypertension, heart disease and stroke were independent risk factors for MCI. Conclusion It is important to enhance the prevention and cure of cerebrovascular diseases.