摘要
为研究糖尿病患者尿微量蛋白的改变及其意义,早期糖尿病肾病组(早期DN组)39例,无肾病的糖尿病组(DM组)46例,对照组20例,测定24小时尿白蛋白(Alb)、尿免疫球蛋白G(IgG)、尿β2—微球蛋白(β2-MG)。结果发现:早期DN组的尿白蛋白排泄率(UAE)、尿IgG、尿β2-MG异常增高,与DM组、对照组比较有显著性意义(P<0.05,P<0.05,P<0.05)。提示:糖尿病患者常规测定尿Alb、IgG、β2-MG,对早期DN的诊断有重大意义。
Objective:to study changes of microproteins in urine and its significance in patients with diabetes mellitus(DM)Method: urinary albumin (Alb),urinary immunoglobulin G(IgG),urinary β 2-microglobulin(β 2-MG)with 24 hours urine in group incipient diabetic nephropathy(DN,39 cases),group DM without nephropathy (46 cases),and group control(20 cases) were measuredThe results showed that urinary albumin excretion rate(UAE),uriary IgG,uriary β 2-MG in group incipient DN were significantly higher than that in group DM without nephropthy and group control(P<005,P<005,P<005)These results suggest that it is significant to measure urinary Alb,IgG,β 2-MG routinely in patients with DM for diagnosis of incipient DN \ \
出处
《广西医学》
CAS
1998年第4期523-525,共3页
Guangxi Medical Journal