1,6-二磷酸果糖治疗病毒性心肌炎临床疗效观察

目的观察l,6-二磷酸果糖治疗小儿病毒性心肌炎的疗效。方法对2006年1月～2008年12月收治的120例小儿病毒性心肌炎随机分为治疗组60例及对照组60例。对照组常规予抗病毒、对症及VitC、ATP静脉滴注,辅酶Q口服,治疗组在此基础上加用1,6-二磷酸果糖,100～250mg/kg静脉滴注,每日一次,两组疗程均为2周。观察其症状体症,CK-MB及cTnI恢复情况并进行疗效评定。结果治疗组与对照组总有救率分别为93.33%与60.87%;并能有效恢复CK-MB及cTnI水平。结论1,6-二磷酸果糖治疗小儿病毒性心肌是有较好疗效,适宜临床运用。

Objective To Observe the treatment of 1,6-diphosphate on children with viral myocarditis. Methods The120 cases of children with viral myocarditis which were treated from January 2006 to December 2008 were randomly divided into treatment group （60 cases） and 60 eases of the control group. The control group of conventional anti-virus, illness and VitC, ATP infusion, oral administration of coenzyme Q, treatment group with 1,6 - diphosphate, both treatments were for 2 weeks. To observe the symptoms of physical disease, CK-MB and cTnI recovery evaluated the efficacy. Results The rescue rates of treatment group and control group were 60.87% and 93.33%; and could effectively restory the levels of CK-MB and eTnI. Conclusion Treated with 1, 6-diphosphate on the children with viral cardiomyopathy is an effective and suitable method for clinical use.