2Sandler SR, Karo W, ed. Polymer Syntheses. New York: Academic Press, 1980, 3. 138-161.
3Katre NV, Knauf MJ, Laird WJ. Chemical modification of recombinant interleukin 2 by polyethylene glycol increases its potency in the murine Meth A sarcoma model. Proc Natl Acad Sci USA, 1987, 84: 1487-1491.
4Carpenter CP, Woodside MD, Kinkead ER, et al. Response of dogs to repeated intravenous injection of polyethylene glycol 4000. Toxicol Appl Pharmacol, 1971, 18: 35-40.
5Abuchowski A, Davis FF. Soluble Polymer-enzyme adducts. In: Holcenberg JC, Ed. Enzymes as drugs. New York: Wiley and Sons Inc, 1981. 367-383.
6Knauf MJ, Bell DP, Hirtzer P, et al. Relationship of effective molecularsize to systemic clearance in rats of recombinant interleukin-2 chemically modified with water-soluble polymers. J Biol Chem, 1988, 263: 15064-15070.
7Savoca K, Wieder K. Modified enzymes with unique properties. In: GB Broun, et al. Eds. Enzyme-Polyethylene glycol adducts. Vol 4. New York: Enzyme Engineering, Plenum Press. 1978. 169-173.
8Mur RE. Preliminary clinical results of combination pegylated interferon α-2b plus ribavirin. In: 35th Annual meeting of the European Association for the Study of the liver. 2000, 19.
9Heathcote EJ, Pockros P, Fried M, et al. The pharmacokinetics of pegylated-40 K interferon in chronic hepatitis C patients with cirrhosis. Gastroen-terology, 1999, 116(Pt2): 3190.
10Glue P. Clinical pharmacology of pegylated Interferon α-2b. In: 35th Annual meeting of the European Association for the Study of the Liver. 2000, 13.
2Wang M,Qiu N,Lu S,et al.Serum hepatitis B surface antigen is correlated with intrahepatic total HBV DNA and cccDNA in treatment-Nave patients with chronic hepatitis B but not in patients with HBV related hepatocellular carcinoma[J].J Med Virol,2012:11:20.
3Rossi E,Adams LA,Ching HL,et al.High biological variation of serum hyaluronic acid and Hepascore,a biochemical marker model for the prediction of liver fibrosis[J].Clin Chem Lab Med,2012:8:1-8.
4Liu YZ,Hou FQ,Ding P,et al.Pegylated interferon alpha enhances recovery of memory T cells in eantigen positive chronic hepatitis B patients[J].Virol J,2012,169(1):274.
5Shen J,Chan HL,Wong GL,et al.Assessment of non-alcoholic fatty liver disease using serum total cell death and apoptosis markers[J].Aliment Pharmacol Ther,2012,36(11/12):1057-1066.
6Afshar RM,Mollaie HR.Detection of HBV resistance to Lamivudine in patients with chronic hepatitis B using zip nucleic Acid probes in kerman,southeast of iran[J].Asian Pac J Cancer Prev,2012,13(8):3657-3661.
7Enrico Rossi,Leon A. Adams,Helena L. Ching,Max Bulsara,Gerry C. MacQuillan,Gary P. Jeffrey.High biological variation of serum hyaluronic acid and Hepascore, a biochemical marker model for the prediction of liver fibrosis[J]. Clinical Chemistry and Laboratory Medicine . 2013 (5)