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癌基因、缺氧与食管鳞癌的关系

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摘要 食管鳞状细胞癌(ESCC)是一种典型的分化缺陷性疾病,鳞状上皮细胞正常分化过程被破坏导致细胞发生恶性转化。ESCC的形成是多因素作用、多基因变化和多阶段发展的过程,细胞增殖及凋亡的动态失衡与ESCC的发病机制密切相关。本文通过探讨癌基因、缺氧和肿瘤增殖之间的内在联系,可进一步了解肿瘤的发病机制,对ESCC的治疗有重要意义。
作者 马臻奇
出处 《青海医药杂志》 2009年第6期89-92,共4页 Qinghai Medical Journal
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