感觉性共济失调型慢性炎性脱髓鞘性多发性神经病

Sensory Ataxia Form of Chronic Inflammatory Demyelinating Polyneuropathy

[目的]探讨感觉性共济失调型CIDP的临床特点和发病机制。[方法]总结19例以深感觉障碍为主要表现CIDP患者的临床资料。[结果]本组患者均主要表现为深感觉障碍性共济失调,病程长,易缓解复发,脑脊液蛋白升高显著,病理改变同一般CI-DP,糖皮质激素远期疗效好。[结论]感觉性共济失调型CIDP是CIDP的一种特殊亚型,发病机理可能是免疫反应主要侵及脊髓背根的深感觉纤维。

[Objective] To explore the clinical characteristics and pathogenic mechanism of sensory ataxia form of GBS. [Methods] To Summarize clinical data of 19 cases with sensory ataxia form of GBS. [Result] The main clinical manifestations were sensory ataxia. The disease relieved and recurred easily and had long course. The protein in CSF increased significantly. Pathological feature was same with general CIDP. Treatment of glucocortieoid was satisfied. [Conclusions] Sensory ataxia form of GBS was one subtype of CIDP. Pathogenic mechanism was perhaps that immunoreaction attacked proproioceptive sense fibre of radix dorsalis.