银杏叶联合洛汀新治疗早期糖尿病肾病疗效观察

Clinical Study of the Combined Treatment of the Ginkgo Leaf Injection and Benazepril with Early Diabetic Nephropathy

[目的]探讨银杏叶联合洛汀新治疗早期糖尿病肾病的疗效。[方法]将90例老年早期糖尿病肾病患者随机分为治疗组45例和对照组45例,两组均采用饮食控制、糖尿病常规治疗,对照组单用银杏叶,治疗组采用银杏叶联合洛汀新治疗,疗程三个月。观察两组尿微量蛋白排出量的变化。[结果]:两组的24小时尿微量蛋白排出量均有所下降,其中以联用组下降更为明显(P<0.01)。[结论]:银杏叶联合洛汀新治疗早期糖尿病肾病疗效明显。

[Objective]To explore the combined curative effect of the ginkgo leaf and benazepril on the early diabetic nephropathy （DN）.[Method]Ninety patients with the early diabetic nephropathy（DN）were randomly divided into single group（n = 45, the gink-go leaf injection 20ml,once a day for 3 months）and combined group（n=45 ,added benazepril 10mg,once a day for 3 months）. The changes in glycosylated hemoglobin（Hbalc） and 24 hour urinary microalbum inuria were observed before and after treatment.[Result]Hbalc remained unchanged throughout the course of the treatment, urinary microalbum inuria decreased in both groups, a more profound reduction was achieved after the combined treatment（P〈0.01）. [Conclusion]The combined treatment of the ginkgo leaf injection and benazepril has effects of decreasing the level of urinary microalbum inuria on the early DN.