新生儿缺氧缺血性脑病围产期相关因素分析

Analysis on perinatal interrelated factors of hypoxic ischemic encephalopathy

目的:分析围产期发生新生儿缺氧缺血性脑病(HIE)的相关因素,为其预防提供依据。方法:回顾性分析110例HIE患儿母亲妊娠期病史及分娩情况的临床资料,并与100例同期出生无HIE新生儿作对照。结果:两组中妊高征、羊水过少、脐带异常、胎儿宫内窘迫及新生儿窒息存在统计学差异(均P<0.05)。结论:加强围产期保健,及时处理妊娠并发症,及早发现和处理胎儿宫内窘迫,避免新生儿窒息,对预防和减少新生儿HIE具有重要意义。

Objective： To analyze the correlation between perinatal factors and hypoxic encephalopathy（HIE） , and provide basis consideration for preventing HIE. Methods ：110 neonates diagnosed as HIE, with control of 100 cases having no HIE were retrospectively compared to analyze the risk factors of HIE. Results ：There was a significant difference of perinatal factors in two groups. HIE was significantly associated with pregnancy induced hupertension, oligohydramnios , umbilical cord abnormalities, fetal intrauterine distress and neonatal asphuxia. Conclusion： Promoting the health care of perinatal peroid, improving the quality of obsitetrics, dealing with pregnancy complications in time, early finding and dealing with fetal intrauterine distress, avoiding neonatal asphysis are important factors contributed to prevent and lower the incidence rate of HIE.