摘要
接触致敏物后出现皮肤发红、风团、瘙痒等表现，称为接触性荨麻疹。根据疾病的发生机制可分为非免疫性、免疫性和不明机制者。非免疫性接触性荨麻疹表现为接触局部出现皮损，往往在数小时内皮疹消退。而免疫性接触性荨麻疹除了局部表现外，常伴有呼吸道和消化道等其他系统受累。该疾病的病因复杂多样，病因治疗较为困难，特异性免疫疗法、抗IgE单克隆抗体可能为该病的治疗带来希望。
Contact urticaria refers to a wheal, itching and flare reaction following external contact with an allergen. According to the pathogenesis of contact urticaria, it can be described in three categories： non-immunological contact urticaria, immunological contact urticaria and undetermined contact urticaria. Non-immunological contact urticaria is typically characterized by local eruptions at the site of exposure that can disappear within several hours. Meanwhile, immunological contact urticaria is manifested not only as local skin lesions but also as the involvement of respiratory system, alimentary system, etc. Since the etiology of contact urticaria is complicated, etiological treatment is difficult, whereas specific immunotherapy and anti-I^E monoclonal antibody might benefit its treatment.
出处
《国际皮肤性病学杂志》
2009年第4期237-239,共3页
International Journal of Dermatology and Venereology
