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血浆凝血四项指标检测与肝病患者病情关系探讨 被引量:6

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摘要 目的探讨血浆凝血四项指标检测与肝病患者病情关系。方法使用血凝仪Sysm exCA-50测定421例肝病患者和30例体检者血浆凝血酶原时间(PT),部分凝血活酶时间(APTT),纤维蛋白原(FIB)和凝血酶时间(TT),并按病情轻重分5组进行比较。结果肝病患者不同病程期凝血四项水平有不同程度的异常,除急性肝炎组与健康对照组之间差异无统计学意义(P>0.05)外,其余各组与对照组比较都存在PT、APTT、TT延长,FIB明显下降,其异常程度呈现重症肝炎>肝炎后肝硬化>慢性活动性肝炎>慢性迁延性肝炎。结论血浆凝血四项指标检测可客观评价肝病患者的凝血功能状况,并且与肝病的严重程度相一致,可以帮助判断肝细胞损害程度。
作者 程圣华 吕亮
出处 《淮海医药》 CAS 2009年第4期330-331,共2页 Journal of Huaihai Medicine
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