多糖对早期断奶仔猪淋巴细胞增殖与细胞因子的影响

Effects of Polysaccharides on Immunologic Functions in Early-weaned Piglets

为探讨多糖对早期断奶仔猪淋巴细胞增殖与细胞因子的影响,选用21d龄健康杜×长×大断奶仔猪(5.30±0.25kg)25头,随机分为5个组,每组5头,分别饲喂玉米-豆粕型基础日粮(CR)、基础日粮+0.3%白术纯多糖(PPAM)、基础日粮+0.6%复合粗多糖(CCP)、基础日粮+0.6%白术粗多糖(CPAM)、基础日粮+抗生素(15%金霉素150mg/kg+4%黄霉素50mg/kg)(ANT),试验期为14d。结果显示:PPAM、CCP能提高血清中TNF的含量(P<0.05),同时PPAM、CCP、CPAM也有提高淋巴细胞增殖和IL-2的趋势。表明饲料中添加PPAM、CCP能够有效提高早期断奶仔猪的免疫力。

To study the effects of polysaccharides on lymphocyte transformation and cytokines in early-weaned piglets, Twenty-five ＂Durocx Landracex Yorkshire＂ crossbred weaned piglets （21th day, 5.30±0.25kg BW） were randomly divided into 5 groups of 5 replicates per treatment and one piglet per replicate, fed with basal diet, basal diet plus 0.3 % pure polysaccharides of atractylodes macrocephala koidz（PPAM）, basal diet pins 0.6% crude compound polysaccharides （CCP）, basal diet plus 0.6% polysaccharides of atractylodes macroeephala koidz （CPAM）, adding antibiotic （15% chlortetracycline 150mg/kg and 4% flavomycin 50mg/kg）（ANT） respectively. The trial lasted for 14 days. The results showed as follows： the serum TNF concentration of the piglets treated with PPAM or CCP were higher （P〈0.05） than those treated with CR; lymphocyte transformation and IL-2 of the piglets treated with PPAM, CPAM and CCP were greater than those treated with CR, but there were no significant differences（P〉0.05） among them. These results indicated that the dietary supplemented with PPAM and CCP can improve some immune indices of early-weaned piglets.