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心率:一个独立的危险因子——现有的证据及基本机制 被引量:5

Heart Rate:an Independent Risk Factor—Current Evidence and Basic Mechanisms
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摘要 很多的流行病学研究提示快心率在一般人群及各种心血管疾病人群中都联系着不良预后,这种联系在心率>80次min-1的时候已经比较明显。随着特异降心率药物的出现,单纯降低心率带来的获益也已经得到证实,另外,很多实验也已表明快的心率可能联系着血流动力学的改变、血管顺应性的下降、血管内皮功能受损、血管炎症反应并可能增加急性冠脉事件的发生。这些证据都表示,心率应该被列入心血管疾病的危险因子。 Mounting epidemiological studies shows elevated heart rate,obviously when 〉 80 byte/miu,is accompanied with poor prognosis in general population and kinds of cardiovaseular patients. Benefits brought by purely slowing down heart rate has been partly proved as the use of medicines specificially decreasing heart rate,further more,many experiments suggests fast heart rate is associated with hemodynamics disturbance,descending vascular compliance, impaired endothelium function, vascular inflammation and may facilitate acute coronary events. In light of these evidences,heart rate should be included among the cardiovascular risk factors.
作者 龚玲 陈晓平
出处 《心血管病学进展》 CAS 2009年第4期634-638,共5页 Advances in Cardiovascular Diseases
关键词 心率 心血管疾病 危险因子 heart rate eardiovascular disease risk factor
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