急性播散性脑脊髓炎的治疗与预后

Research Progress of Treatment and Prognosis in Acute Disseminated Encephalomyelitis

急性播散性脑脊髓炎是由感染或疫苗接种触发，T细胞介导的针对髓鞘碱性蛋白的自身免疫反应。某些非特异性免疫抑制疗法用于该病的治疗，对患者的预后是有益的，减少长期的致残率。本文就近几年来该病的治疗、预后及是否发展成多发性硬化的预测性因子的研究予以综述。

Acute disseminated encephalomyelitis（ADEM） is a T cell mediated autoimmune response to myelin basic protein triggered by an infection or vaccination. Some nonspecific immunosuppressant therapies are used for ADEM and shown to be beneficial in reducing long-term disability. This article reviewed the advance of treatment, prognosis and prognostic factors that determined ADEM patients will develop multiple sclerosis.