原发中枢神经系统淋巴瘤17例

Chlinic Analysis of Primary Center Nervous Lymphoma

目的探讨原发中枢神经系统淋巴瘤的治疗方法和预后。。方法回顾性分析了17例患者。按AnnArbor分期标准,IE期3例,IIE期9例,Ⅲ-Ⅵ期5例。结果全组5年生存率为47.1%,IE、IIE期5年生存率分别为66.7%和40.0%,Ⅲ-Ⅵ期5年生存率为0。结论经综合治疗,中枢神经系统淋巴瘤的预后明显改善。建议对早期中枢神经系统淋巴瘤进行正规、足量、联合化疗。

Objective To explore the prognosis of patients with Primary center nervous lymphoma. Methors In the period of 1995 to 2002, 17 patients with Primary center nervous Iymphoma were treated and the therapentre effects were reviewed. There were three patients in stage Ⅰ, nine in stage Ⅱ, and five patients in stage Ⅲ and Ⅳ. Results The fiveyear survival rates were 47.1%, while the 5 - year survival rates by stage were 66.7%, 40.0% for stage Ⅰ, Ⅱ respectively and 0 for stage Ⅲ and Ⅳ. Conclusion The prognosis of primary Primary Primary center nervous Iymphoma get better affcter multi - modality treatment, and postorchidecto my chemotherapy is necessary for stage Ⅰ and stage Ⅱ patients.