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早期胃癌行前哨淋巴结定位活检的临床意义

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摘要 目的探讨前哨淋巴结活检技术在早期胃癌中的临床意义。方法68例早期胃癌术中亚甲蓝定位活检前哨淋巴结,术后行常规HE病理检查及AE1或AE3免疫组化检查。结果68例中66例检出SLN,检出率为97.1%。由SLN状态预测胃周淋巴结转移情况的准确率为93.9%(62/66),敏感性为88.9%(32/36),特异性为100.0%(32/32),假阴性率为11.1%(4/36)。免疫组化法与常规HE法对SLN转移的检出率相比较,差异有统计学意义(P=0.034),免疫组化法共检出24枚或16例SLN存在微转移现象。结论SLN能较准确反映早期胃癌的淋巴结转移状况,AE1或AE3免疫组化法较常规HE病理检查更为敏感,对确定临床分期、诊疗及判断预后有积极临床意义。
出处 《菏泽医学专科学校学报》 2009年第2期16-18,共3页 Journal of Heze Medical College
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