加速康复外科处理对结直肠癌手术后血乳酸水平的影响

Changes of blood lactate levels after colorectal cancer resection with fast-track surgery

目的观察加速康复外科理念指导下结直肠癌手术后血乳酸水平的改变及临床意义。方法对我院2008-01～2008-12期间80例结直肠癌手术患者,随机分成2组,比较加速康复组35例患者和常规对照组45例患者术前及术后1,6,12,24,48h动脉血乳酸水平变化。结果加速康复组在术后1,6,12,24h的动脉血乳酸水平较常规对照组明显降低(P<0.01),术后48h基本降至术前水平,两组比较无明显差异。结论加速康复外科理念指导下的行之有效、成熟的围手术期操作程序能够降低患者术后血乳酸水平,促进患者术后恢复。

Objective To observe the blood levels of lactic acid after colorectal cancer resection with fast-track surgery. Methods Levels of lactatic acid in arterial blood of 35 patients after colorectal cancer resection with fast-track surgery and 45 patients after colo- rectal cancer resection with traditional method were observed at hour I, 6,12,24,48 after operation. Results The level of lactatic acid in patients with fast-track surgery was significant lower than that of patients with traditional method at hour 1,6, 12,24 （P 〈 0.01 ）. Conclusion A continuous decline of blood lactatic acid in patients after eolorectal cancer resection is related to a favorable fast-track surgery course. Fast-track concepts are feasible for colorectaJ surgery, with accelerated convalescence and excellent patient satisfaction.