早产儿喂养不耐受影响因素分析

An analysis of risk factors in preterm infants with feeding intolerance

目的探讨与早产儿喂养不耐受相关的危险因素。方法对我院2007年1月—12月收治的203例早产儿作回顾性分析。结果早产儿喂养不耐受的发生率为41.38%。喂养不耐受组胎龄和出生体质量较非喂养不耐受组明显低,差异有统计学意义(P<0.05);宫内窘迫、窒息、宫内感染及呼吸机治疗率喂养不耐受组分别为65.48%、48.81%、46.43%、44.05%,显著高于非喂养不耐受组39.50%、25.21%、25.21%、29.41%(P<0.05);胎龄小、出生体质量低、宫内窘迫和窒息是早产儿喂养不耐受的危险因素。结论早产儿喂养不耐受与多因素有关,预防产前及生后各危险因素,有利于改善早期胃肠道喂养耐受性。

Objective To study the related risk factors in preterm infants with feeding intolerance. Methods We retrospectively analyzed the data of 203 pretenn infants in our hospital from January 2007 to December 2007. Results The incidence of feeding intolerance was 41. 38%. Gestational age and birth weight of pretenn infants in feeding intolerance group were significantly lower than non-feeding intolerance group （ P 〈 0. 05 ） ; There were more happen of intrauterine hypoxia, asphyxia, intrauterine infection and mechanical ventilation in feeding intolerance group （65. 48% , 48.81% , 46. 43% , 44.05% ） than in non-feeding intolerance group （39.50% , 25.21% , 25.21% , 29.41% ）, the difference was statistically significant. It was found that risk factors related to feeding intolerance were small gestational age, low birth weight, intrauterine hypoxia and asphyxia. Conclusion The cause of feeding intolerance in preterm infants are multi-factorial. We will improve enteral feeding in earlier period by prevented all risk factors.