银杏达莫注射液治疗早期糖尿病肾病的临床观察

Clinical Observation on Early Stage DM Type Nephropathy Treatment by Using Yinxingdamo Injecta

目的探讨银杏达莫注射液对早期糖尿病肾病的治疗作用。方法将78例早期糖尿病肾病患者随机分为对照组40例和治疗组38例,对照组采用常规治疗,治疗组在常规治疗的基础上加用银杏达莫注射液,疗程5周,分别测定两组治疗前后的尿白蛋白排泄率(UAER)、空腹血糖(FBG)、血肌酐(Scr)和血脂指标的变化。结果与对照组比较,治疗组治疗后UAER明显降低(P<0.01),Scr、血脂指标改善(P<0.05或P<0.01),而两组FBG无明显差异(P>0.05)。结论银杏达莫注射液可减少尿蛋白,改善肾功能,对早期糖尿病肾病具有治疗作用。

Objective To investigate effection on early stage DM type nephropathy treatment by using Yinxingdamo injecta. Methods Randomly divided the 78 patients into comparison team 40 patients and treatment team 38 patients. Comparison team by normal treatment, and the treatment team using Yinxingdamo inject a additionally except normal treatment. Treatment period 5 weeks, and measuring the change of urine protein,UAER,FBG, Scr and blood-fat index before and after treatment. Results Comparing with the comparison team,the treatment team could be seen obviously decrease of UAER（P〈 0.01 ）, and the Scr, blood-fat index improved（P〈 0.05 or P〈 0.01 ）. And not obvious difference of FBG between two teams（P〉0.05）. Conclusion Yinxingdamo injecta can decrease the urine protein, improve the kidney function, and have curative effect on early stage DM type nephropathy.