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放射性^125I粒子植入治疗肺肿瘤52例

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摘要 目的探讨放射性^125I粒子植入治疗肺肿瘤的方法和效果。方法2004年8月至2008年12月应用放射性^125I粒子植入治疗肺肿瘤患者52例,应用近距离照射计划系统(TPS)和实时计划相结合,确定粒子的分布、活度、数量、肿瘤匹配周边剂量(MDP),在CT引导下经皮穿刺植入放射性^125I粒子,术后1、2、6个月分别行CT扫描观察肿瘤大小,化验血象、肝肾功能,评估生活质量(Karnofsky评分)。结果肿瘤从1个月至第6个月开始逐减缩小甚至消失,52例56处病灶51例有效,有效率91.1%,而对血象、肝肾功能影响不大,Kamofsky评分提高。结论合理分布的^125I粒子永久性植入治疗肺肿瘤,能使肿瘤明显缩小,放射损伤小,对改善临床症状、提高生活质量有效,是肺肿瘤有效的综合治疗手段之一。
作者 吴喜宏 薄涛
出处 《肿瘤研究与临床》 CAS 2009年第7期492-494,共3页 Cancer Research and Clinic
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  • 1Cady B,Jenkins RL,Steele GD Jr,et al.Surgical margin in hepatic resection for colorectal metastasis:a critical and improvable determinant of outcome.Ann Surg,1998,227:566-571.
  • 2Rieber A,Brambs HJ,Kauffmann G,et al.Combined intra-arterial chemotherapy and radiotherapy in inoperable non-small cell bronchial carcinoma.Strhlenter Onkol(German),1991,167:14-18.
  • 3Miyaji N,Oyama T,Uchiyama N,et al.Results of radiotherapy combined with BAI(bronchial artery infusion) for non-small cell lung cancer--analysis of 104 cases. Nippon Igaku Hoshasen Gakkai Zsshi(Japanese),1991,51:270-281.
  • 4Murakami M,Kuroda Y,Sano A,et al.Therapeutic results of non-small cell lunch cancer in stager Ⅲ:combined synchronous irradiation with bronchial artery infusion of CDDP. Nippon Igaku Hoshasen Gakkai Zasshi(Japanese),1995,55:44-49.
  • 5Zelefsky MJ, Hollister T, Raben A, et al. Five-year biochemical outcome and toxicity with transperineal CT-planned permanent I-125 prostate implantation for patients with localized prostate cancer. Int J Radiat Oncol Biol Phys,2000,47:1261-1266.
  • 6Willins J, Wallner K. CT-based dosimetry for transperineal I-125 prostate brachytherapy. Int J Radiat Oncol Biol Phys,1997,39:347-353.
  • 7Molloy JA, Williams MB. Treatment planning considerations and quality assurance for CT-guided transischiorectal implantation of the prostate. Med Phys,1999,26:1943-1951.
  • 8Martinez-Monge R, Nag S, Nieroda CA, et al. Iodine-125 brachytherapy in the treatment of colorectal adenocarcinoma metastatic to the liver. Cancer,1999,85:1218-1225.
  • 9Vikram B, Mishra S.Permanent iodine-125 implants in postoperative radiotherapy for head and neck cancer with positive surgical margins. Head Neck,1994,16:155-157.
  • 10Kumar PP, Patil AA, Leibrock LG,et al. Continuous low dose rate brachytherapy with high activity iodine-125 seeds in the management of meningiomas. Int J Radiat Oncol Biol Phys,1993,25:325-328.

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