烧伤早期创面病原菌的分布特点及耐药性分析

Investigation of infectious bacteria in early burn wound and analysis of their antibiotic resistance

目的了解笔者单位近6年来烧伤早期创面病原菌的分布特点及耐药情况。方法收集2002至2008年笔者单位238例烧伤患者创面分泌物标本中分离的病原菌,对其菌种分布特点及耐药性进行分析。结果革兰阳性菌283株,其中金黄色葡萄球菌的菌株数居首位,以耐甲氧西林金黄色葡萄球菌(MRSA)居多,表皮葡萄球菌和粪肠球菌的菌株数分别位居第2、3位;革兰阴性杆菌254株,其中鲍氏不动杆菌的菌株数居首位,阴沟肠杆菌和铜绿假单胞菌的菌株数分别位居第2、3位;另外检出真菌9株。结论笔者单位烧伤早期创面病原菌的分布情况与以前有所不同,可能与MSRA呈多重耐药性以及鲍氏不动杆菌产生的超广谱β内酰胺酶有关。

Objective To study the infectious strains of bacteria in our early burn patients in recent 6 years, and analyze their antibiotic resistance. Methods Bacteria were isolated from the wound excretions of 238 burn patients hospitalized during 2002 to 2008 for analyzing their strains and their antibiotic resistance. Results 283 strains were Grams positive bacteria, among them staphylococcus aureus was the predominant strain. Further analysis that methicillin resistant staphylococcus aureus （MRSA） ranked the first in occurrence, followed by methicillin-resistance Staphylococcus epidermidis （MRSE）and Enterococcus fecalis, 254 strains were Gram negative bacteria, and among them Acinetobacter baumarinii was predominant, and Enterobacter cloacae and Pesudomonas aeruginosa rahked the 2nd and 3rd. Nine strains were fungis. Conclusion Investigation of infectious bacteria in early burn wound is different in our ward. It may be related to multiple - drug - resistance of MRSA and the β- laetamases from acinetobacter baumannii.