维生素A对婴幼儿哮喘的作用

Therapeutic effect of vitamin A on infants with asthma

目的:观察维生素A(VitA)佐治婴幼儿哮喘的临床疗效。方法:80例哮喘患儿分为VitA辅助治疗组(40例)和常规治疗组(40例),并选取40例健康婴幼儿作为对照组。检测比较所有婴幼儿的血清VitA水平。两组哮喘患儿均给予糖皮质激素、支气管扩张剂吸入治疗,VitA辅助治疗组加用VitA,观察两组患儿哮喘发作程度的变化并进行疗效评价。结果:与常规治疗组比较,VitA辅助治疗组哮喘发作程度、临床疗效差异有统计学意义(P<0.05)。结论:VitA可降低婴幼儿哮喘发作频率,减轻哮喘发作程度,可用于佐治婴幼儿哮喘。目的:观察维生素A(VitA)佐治婴幼儿哮喘的临床疗效。方法:80例哮喘患儿分为VitA辅助治疗组(40例)和常规治疗组(40例),并选取40例健康婴幼儿作为对照组。检测比较所有婴幼儿的血清VitA水平。两组哮喘患儿均给予糖皮质激素、支气管扩张剂吸入治疗,VitA辅助治疗组加用VitA,观察两组患儿哮喘发作程度的变化并进行疗效评价。结果:与常规治疗组比较,VitA辅助治疗组哮喘发作程度、临床疗效差异有统计学意义(P<0.05)。结论:VitA可降低婴幼儿哮喘发作频率,减轻哮喘发作程度,可用于佐治婴幼儿哮喘。

Objective To observe the clinical effect of vitamin A on infants with asthma. Methods 80 infants with asthma were assigned to receive inhalation of glucocorticoid and bronchodilator （conventional therapy group, n = 40） or conventional therapy plus vitamin A treatment （VitA group, n = 40）. Changes of the degree of asthma in the two groups were observed and the efficacies of the treatments were evaluated. Another 40 cases of healthy infants were included as control group. The serum levels of vitamin A in the three groups were measured. Result There were significant differences in the degree of asthma and clinical efficacy between conventional therapy group and VitA group （P 〈 0.05）. Conclusion Vitamin A can reduce the incidence of asthma and relieve the degree of asthma in infants.