含硫氨基酸与微量元素锰对肉鸡胫骨软骨症的影响

Excess Levels of Sulfur Amino Acid and Manganese Induce Tibial Dyschondroplasia in Broiler

采用半纯合饲粮（Ｍｎ１．７ｍｇ／ｋｇ）研究过量含硫氨基酸（ＳＡＡ，为推荐量１１．４８ｇ／ｋｇ的１．５倍）与过量锰（Ｍｎ，为需要量６０ｍｇ／ｋｇ的２倍）对肉鸡胫骨软骨症（ＴＤ）的影响。试验将９６只１日龄ＡＡ肉雏鸡随机分为４组，即ＳＡＡ与Ｍｎ常量组（１１．４８ｇ／ｋｇ和６１．７ｍｇ／ｋｇ），过量ＳＡＡ与常量Ｍｎ组（１７．１８ｇ／ｋｇ和１２１．７ｍｇ／ｋｇ），常量ＳＡＡ与过量Ｍｎ组（１１．４８ｇ／ｋｇ和１２１．７ｍｇ／ｋｇ）和过量组（１７．１８ｇ／ｋｇ和１２１．７ｍｇ／ｋｇ）。试验２１ｄ的结果表明，过量ＳＡＡ抑制肉鸡生长、胫骨变长，诱导肉鸡ＴＤ的发病率升高；高锰日粮使肉鸡肝、肾、胰、血浆、心、肌肉组织中锰含量升高，诱导肉鸡ＴＤ的发病率上升；当日粮中过量ＳＡＡ和过量锰同时存在时，肉鸡生长的降低加剧，肝、肾、胰、血浆锰含量下降，胫骨长度增加，骨灰含量下降，诱导肉鸡ＴＤ的发病率更为严重。

An experiment was conducted by semi-purified diet to investigate the effect of excessive sulfur amino acid(SAA) and manganese(Mn)on tibial dyschondroplasia(TD)in commercial broilers from one-day to 21 days of age.The design of experiment treat as follows:normal SAA (11.48 g/kg) and Mn(61.7 mg/kg),excessive SAA (17.18 g/kg)and normal Mn (HSNMn:SAA is 1.5 times more than requirement recommendation relative to Lys),normal SAA and excessive Mn (121.7 mg/kg),excessive SAA (17.18 g/kg)and excessive Mn(121.7 mg/kg),There were significant effects of excessive SAA on body weight,feed conversion efficiency,bone ash,induced tibial length,and finally induced TD(P<0.01).Excessive Mn increased concentrations of tissue Mn determined such as bone,liver,kidney,pancreas,heart and muscle(P<0.01 or P<0.05),and induced TD(P<0.01).The results shows that excess levels of SAA and Mn markedly exacerbate TD-induced and body weight-lessened in broiler chickens(P<0.01).