1Newton H B. Neurological complications of syste miccancer[J]. Am Fam Phys, 1999, 59: 878.
2Lutterbach T, Cyron D, Henne K, et al. Radiosurgery followed by planned observation in patients with one to three brain metastases[J]. Neurosurg, 2003, 52: 1066.
3Tan T C, Black P M. Image-guided craniotomy for cerebral metasta-ses: Techniques and outcomes[J]. Neurosurg, 2003, 53: 82.
4Lesser G J. Chemotherapy of cerebral metastases from solidtumors[J]. Neurosurg ClinNAm, 1996, 7: 527.
5FranciosiV, CocconiG, MichiaraM, et al. Front-linechemo therapy with cisplatin and etoposide forpatients with brain metas tases from breastcarcinoma, nonsmall celllung carcinoma, ormalignan tmela-noma: aprospective study[J]. Cancer, 1999, 85(7): 1599.
6Bernardo G, Cuzzoni Q, Strada M R, et al. First-linechemo therapy with vinorelbine, gemcitabine, and carboplatin in the treatmentof brain metastas esfrom non-small·-celllung can cer: a phase IIstudy[J]. CancerInvest, 2002, 20(3): 293.
7Robinet G, Thomas P, Breton J L, et al. Results of aphase Ⅲ study of earlyvets usd elayed whole brainradio thera pywith concur rentcispl-atin and vinorelbine combination in inoperable brain metastasis of non-small-celllungcancer: Groupe Francisde Pneumo-Cancerologie(GFPC) Protocol95-l[J]. AnnOncol, 2001, 12(1): 59.
8Oberhof C, Kieback D G, Wurstlein R, et al. Topotecan chemother-apyinpatients with breast cancer and brainmet astases: resultsofa pilotstudy[J].Onkologie, 2001, 24(3): 256.
9Abrey L E, Olson J D, Raizer J J, et al. A phaseIItrial of temozolo-midefor patients with recurrentor progressive brainmetastases[J]. J Neurooncol, 2001, 53(3): 259.
10Christodoulou C, Bafaloukos D, Kosmidis P, et al. PhaseI Istudy of temozo 10 mideinheavily pretreate cancerpatients with brainmetasta. ses[J]. AnnOncol, 2001, 12(2): 249.
4Park HC, Seong J, Han KH,et al. Dose-response relationship in local radiotherapy for hepetocellular carciuma [J]. Int J Radiat Oncol Biol Phys,2002,54(1) :150-155.
5HE B P, WANG J J, ZHANG X, et al. Differential reactions of microglia to brain metastasis of lung cancer[J]. Mol Med, 2006, 12(7-8):161-170.
6BAI Y, LIU R L, HUANG D, et al. CCL2 recruitment of IL-6-producing CDllb+ monocytes to the draining lymph nodes during the initiation of Thl 7-dependent B cell-mediated autoimmunity[J]. Eur J Immunol, 2008, 38(7):1877-1888.
7ZHANG M, OLSSON Y. Reactions of astrocytes and microglial cells around hematogenous metastases of the human brain. Expression of endothelin- like immunoreactivity in reactive astrocytes and activation of microglial cells[J]. Neurol Sci, 1995, 134(1-2):26-32.
8SINGH S, GUPTA A K. Nitric oxide: role in tumour biology and iNOS/ NO-based anticancer therapies[J]. Cancer Chemother Pharmacol, 2011, 67 (6):1211-1224.
9HERNANDEZ J, COOPER J, BABEL N, et al. TNFalpha gene delivery therapy for solid tumors[J]. Expert Opin Biol Ther, 2010, 10(6):993-999.
10PINTO A, MERINO M, ZAMORA P, et al. Targeting the endothelin axis in prostate carcinoma[J]. TumourBiol, 2011, [Epub ahead of print].