重症肌无力的治疗:循证与辨证

The management of myasthenia gravis:evidence-based or pathophysiology-based?

通过1例重症肌无力(MG)患者的病情分析,提出临床处理需要解决的问题,并对比有关MG治疗的循证医学证据和指南与实际治疗之间存在的差距。经过比较,发现现有的循证医学证据不足以充分解决MG的治疗问题。以上分析提示我们重症肌无力的治疗需要结合循证医学证据,但更需要在充分理解病理生理学的基础上给予合理的治疗。

After the introduction of a cases of myasthenia gravis （MG） , the questions related to clinical management were raised, and the differences between evidence and guidelines on MG management and practical managements were compared. Through comparison, it was found that current evidence-based measures were not enough to solve the problems of clinical management for MG. It is suggested that in addition to the current evidence, we should give reasonable managements on the basis of thorough understanding of the patho- physiology of MG.