多发性硬化和实验性自身免疫性脑脊髓炎中的轴突损伤
被引量：2
摘要
本文综述了多发性硬化和实验性自身免疫性脑脊髓炎中轴突损伤的研究进展,包括疾病早期、起始阶段的轴突损伤及其机制,影像及组织学表现正常的白质内的轴突变性,多发性硬化灰质内的轴突损伤,长病程多发性硬化病变内的轴突缺失等方面,并提出可能的干预措施及存在的问题。
出处
《国际神经病学神经外科学杂志》
2009年第3期271-275,共5页
Journal of International Neurology and Neurosurgery
参考文献24
-
1Linker RA, Sendtner M, Gold R. Mechanisms of axonal degeneration in EAE--lessons from CNTF and MHC I knockout mice. J Neurol Sci, 2005, 233(1-2) : 167-172.
-
2Charcot JM. Histologie de la sclerose en plaques. Gazette H ? pitaux, 1868b, 41 (566) : 557-558.
-
3Hauser SL, Oksenberg JR. The neurobiology of multiple scle- rosis : genes, inflammation, and neurodegeneration. Neuron, 2006, 52 (1) : 61 -76.
-
4Sherman DL, Tait S, Melrose S. Neurofascins are required to establish axonal domains for salutatory conduction. Neuron, 2005, 48(5) : 737-742.
-
5Mathey EK, Derfuss T, Storch MK, et al. Neurofascin as a novel target for autoantibody-mediated axonal injury. J Exp Med, 2007, 204(10): 2363-2372.
-
6Maggs FG, Palace J. The pathogenesis of multiple sclerosis: is it really a primary inflammatory process? Mult Scler, . 2004, 10(3) : 326-329.
-
7Tsunoda I, Tanaka T, Terry EJ. Contrasting roles for axonal degeneration in an autoimmune versus viral model of multiple sclerosis. Am J Pathol, 2007, 170(1) : 214-226.
-
8Pascual AM, Martinez Bisbal MC, Bosca I, et al. Axonal loss is progressive and partly dissociated from lesion load in early multiple sclerosis. Neurology, 2007, 69 ( 1 ) : 63-67.
-
9De Vfies GH. Cryptic axonal antigens and axonal loss in multiple sclerosis. Neurochem Res, 2004, 29 ( 11 ) : 1999- 2006.
-
10Kassmann CM, Lappe Siefke C, Baes M, et al. Axonal loss and neuroinfiammation caused by peroxisome-deficient oligodendrocytes. Nat Genet, 2007 , 39 ( 8 ) : 969-976.
同被引文献40
-
1曹翠丽,马常升,阎蕴力,杨天祝,李学平.实验性变态反应性脑脊髓炎大鼠丛上细胞扫描电镜观察[J].解剖学杂志,2003,26(6):591-594. 被引量：1
-
2付文祥.细胞凋亡与自身免疫病[J].免疫学杂志,2005,21(B06):85-88. 被引量：4
-
3董梅,刘瑞春,郭力,李春岩.Wistar大鼠多病程实验性变态反应性脑脊髓炎的模型建立[J].中国免疫学杂志,2006,22(1):78-81. 被引量：12
-
4郑建筝,高聪,谢富华,蒲蜀湘,陈盛强.SD大鼠实验性变态反应性脑脊髓炎模型的建立[J].实用诊断与治疗杂志,2006,20(7):469-472. 被引量：10
-
5Mancardi G, Hart B A, Capello E, et al. Restricted immune re- sponses lead to CNS demyelination and axonal damage [J]. J Neuroimmunol, 2000,107(2) : 178-183.
-
6Linker R A, Sendmer M, Gold R. Mechanisms of axonal degen- eration in EAE-lessons from CNTF and MHC I knockout mice [J]. J Neurol Sci, 2005,233(1-2) :167-172.
-
7Mancardi G, Hart B A, Capello E, et al. Restricted immune re- sponses lead to CNS demyelination and axonal damage [J]. J Neuroimmunol, 2000,107(2) :178-183.
-
8E I Behi M, Dubucquoi S, Lefranc D, et al. New insights into cell responses involved in experimental autoimmune encephalomyelitis and multiple sclerosis [J]. Immunol Lett, 2005,96 (1) : 11-26.
-
9Suvannavejh G C, Dal Canto M C, Matis L A, et al. Fas-media- ted apoptosis in clinical remission of relapsing experimental auto- immune encephalomyelitis [J]. J Clin Invest, 2000, 105 (2) 223-231.
-
10Kountouras J, Zavos C, Chatzopoulos D. Apoptosis and autoim- munity as proposed pathogenetic links between Helicobacter pylo- ri infection and idiopathic achalasia[J]. Med Hypotheses, 2004, 63(4) : 624-629.
-
1刘绛光,王晓辉,张宏,黄姝杰.实验性自身免疫性重症肌无力动物模型(综述)[J].中国神经免疫学和神经病学杂志,2005,12(2):90-92. 被引量：6
-
2鄂亚军,伍建林.磁共振检查在多发性硬化诊断中的应用进展[J].国外医学（临床放射学分册）,2006,29(2):105-107. 被引量：2
-
3杨炼红,吴照明.青霉素致大鼠急性癫痫模型的构建[J].岭南急诊医学杂志,2010(1):1-3. 被引量：1
-
4唐冰杉,杨明山,曹学兵.实验性自身免疫性重症肌无力动物模型的研究概况[J].国外医学（神经病学．神经外科学分册）,2002,29(3):265-268. 被引量：3
-
5牛凤云,陈会娟,巩昭勇,贾维刚,赵丽丽.实验性自身免疫性重症肌无力动物模型研究概况[J].中华中医药学刊,2009,27(4):787-788. 被引量：1
-
6汪志超,赵研,张毅.脊髓多发性硬化的MRI诊断分析[J].蚌埠医学院学报,2013,38(4):459-460. 被引量：1
-
7王雪笠,贺银方,冯连元.应用多导睡眠图对80例睡眠障碍进行原因探讨[J].临床误诊误治,2007,20(4):44-45. 被引量：2
-
8钱丽霞,刘起旺,张锁旺,梁力,孙少杰.脊髓多发性硬化的MRI诊断[J].临床放射学杂志,2001,20(12):899-901. 被引量：2
-
9刘俊豪,姚欣强,黄祖成,黄志平,吴晓亮,吴秀华,季伟,孔刚刚,李榕,朱青安.兔颈脊髓半侧挫伤模型的建立及其MRI和组织学表现的研究[J].中国临床解剖学杂志,2017,35(1):31-36. 被引量：3
-
10陈建明,蒋耀光,范士志,王如文,李志平,王东伟.小儿重症肌无力的外科治疗[J].中国胸心血管外科临床杂志,2000,7(1):7-9. 被引量：11
